Robert Otto Becker, MD (1923 – 2008) – 5 decades of electromedical research by a man far, far ahead of his time.
The father of electrotherapy and electrochemically induced cellular regeneration; a pioneer of silver plated nylon bandage in chronic wound care and regeneration of tissue. His entire bibliography with links to PubMed is offered for your education and not intended as promotional material for EarthPulse™.
In the 1970’s Becker warned that power frequency and radio wave fields were damaging to health. He lost his research funding and was forced out of the Veterans Administration Hospital in Syracuse University. If anyone deserved a Nobel in medicine, it was Bob, but they couldn’t allow a Nobel prize to a man warning about dangers of EMF. Little did he know that EMF’s were going to destroy the sleep patterns of all planetary inhabitants,
In our conversations between 2004 and 2007 when presented with the NASA Goodwin studies, he concurred that 10 Hz may just have some ‘magical’ effect. He died shortly after. It wasn’t until 2008 that I’d come up with MoreATP; The Mitochondrial Theory of Aging in Reverse how to enhance sleep, recovery, longevity and physical & mental performance very simply with pulsed magnetic fields.
Robert O. Becker: Complete in-vitro regeneration of adult fingertip with intact finger print, finger nail and tactile sensation.
Photo’s below as submitted in support of patent filing
Robert O. Becker: Regeneration of tissue in diabetic ulcer. Becker chose amputate candidates for his research on chronic ulcers and NEVER lost a limb.
100% success during more than a decade of research.
(Use the PMID to find source on PubMed)
Becker RO, Exploring new horizons in electromedicine, Journal of Alternative Complementary Medicine 2004 Feb;10(1):17-8., PMID: 15025873
Becker RO, Induced dedifferentiation: a possible alternative to embryonic stem cell transplants, NeuroRehabilitation. 2002;17(1):23-31, PMID: 12016344
Department of Orthopedic Surgery, Upstate Medical Center, State University of New York, Syracuse, NY 13210, USA.
Induction of local tissue regeneration in the human would best be accomplished if the patient’s own cells at the desired site could be caused to dedifferentiate into the required embryonic stem cells. A system involving the electrical iontophoretic introduction of free silver ions into human wounds for their antibiotic effect has been in clinical use since 1975. In addition to a major antibiotic effect, the technique was found to produce the regeneration of all local tissues, apparently by stimulating dedifferentiation of mature human cells. More recently the use of a newly developed silvered nylon fabric has been found to have similar results without the need for electrical parameters. The results of a preliminary laboratory and clinical study of this material are presented.
Becker RO, Silver ions in the treatment of local infections, Met Based Drugs,1999;6(4-5):311-4., PMID: 18475906, PMCID: PMC2365176
Department of Orthopaedic Surgery State University of New York Health Science Center at Syracuse 550 Harrison Street Syracuse New York 13202 USA.
A study of the use of free silver ions as an antibacterial and antifungal agent administered to infected local wounds has been conducted over the past two decades. A variety of iontophoretic techniques has been employed utilizing either pure silver wires or several types of silvered nylon fabrics as anodes in a direct current electrical circuit. A new type of silver nylon has recently been evaluated for the same use without iontophoretic current. In vitro studies of both techniques have demonstrated an effective, broad spectrum antibiotic effect including most silver-resistant strains. Over 100 cases of recalcitrant osteomyelitis have been treated with an overall success rate of approximately 65% and no evidence of argyria.
Becker RO, Electromagnetism and the revolution in medicine, Acupuncture & Electro-therapeutic Research ,1987;12(1):75-9., PMID: 2883840
Becker RO, Esper C., Electrostimulation and undetected malignant tumors, Clinical orthopaedics and related research,1981 Nov-Dec;(161):336-9, PMID: 7198021
Webster DA, Spadaro JA, Becker RO, Kramer S., Silver anode treatment of chronic osteomyelitis, Clinical Orthopedics and Related Research, 1981 Nov-Dec;(161):105-14., PMID: 6975686
Twenty-five patients with active, chronic osteomyelitis, resistant to conventional management, were treated with surgical debridement and daily application of electrically activated silver dressings. Sixteen (64%) cases resulted in closed, stable, pain-free wounds, with the remainder resulting in persistent drainage or amputation. Nine of 12 cases complicated by nonunion achieved union. In 13 patients an open-bone graft was performed and silver treatment continued: these tended to remain free of purulent drainage but fared no better than average in the long-term follow-up. The silver anode dressing seems to be an effective aid in the treatment of chronic bone infection when combined with adequate surgical debridement, thereby reducing the need for prolonged systemic antibiotics.
Perry FS, Reichmanis M, Marino AA, Becker RO, Environmental power-frequency magnetic fields and suicide, Health physics, 1981 Aug;41(2):267-77, PMID: 7275611
Marino AA, Cullen JM, Reichmanis M, Becker RO, Hart FX, Sensitivity to change in electrical environment: a new bioelectric effect, The American journal of physiology, 1980 Nov;239(5):R424-7, PMID: 7435656
The action of a 60-Hz, 5 kV/m electric field on erythrocyte parameters in mice was determined. No effects attributable to the magnitude of the field were found, but a transition either from or to an environment containing the field caused decreased red blood cell concentrations and decreased hematocrits. The failure of others to observe effects on erythrocyte parameters following exposure to low-frequency electric fields may have been due to an inappropriate choice of duration of exposure.
Marino AA, Spadaro JA, Fukada E, Kahn LD, Becker RO, Piezoelectricity in collagen films, Calcified Tissue International, 1980;31(3):257-9, PMID: 6781732
Tissue collagen exhibits several levels of structural organization, and this complicates efforts to determine the origin of its piezoelectricity. We made collagen films-by evaporation and electrodeposition from solution-and examined the relation between collagen’s piezoelectricity and its electron microscopic appearance. We found that the electrodeposited films were more organized and exhibited higher piezoelectric coefficients than the evaporated films. Despite this, the evaporated films were piezoelectric, thereby suggesting that the effect originates either at the level of the tropocollagen molecule or, at most, with aggregated structures no larger than 50 A in diameter.
Marino AA, Cullen JM, Reichmanis M, Becker RO, Fracture healing in rats exposed to extremely low-frequency electric fields, Clinical Orthopedics and Related Research, 1979 Nov-Dec;(145):239-44, PMID: 317035
Fibular osteotomies in rats were exposed to an extremely low frequency field for 14 days. By histologic evaluation it was found that the healing rate was retarded by the field. The effect (which was replicated) occurred at much lower power levels than are presently employed in electrical osteogenesis.
Spadaro JA, Becker RO, Function of implanted cathodes in electrode-induced bone growth, Medical & Biological Engineering & Computing, 1979 Nov;17(6):769-75, PMID: 317920
Spadaro JA, Webster DA, Becker RO, Silver polymethyl methacrylate antibacterial bone cement, Clinical Orthopedics and Related Research, 1979 Sep;(143):266-70, PMID: 509832
An improved antibacterial bone cement was sought based on the addition of low concentrations of inorganic silver compounds to polymethyl methacrylate. Composites with AgCl, Ag-AgCl, Ag2O, Ag2SO4 and Ag3PO4 in concentrations of 0.05% to 1% by weight, were tested in vitro against bacterial cultures. All were effective, but Ag2SO4 was especially so, even after 7 weeks of incubation in normal saline. Compressive strength of the cement was not affected by these additions, except in the case of Ag2O. Biocompabibility tests in rabbit muscle for up to 12 weeks showed no significant difference between the Ag -PMM and plain PMM in tissue reactivity, both being minimal. These features, coupled with the broad spectrum of antibacterial activity and low allergic potential of silver, make Ag-PMM an attractive alternative to conventional organic antibiotic/bone cement composites.
Reichmanis M, Marino AA, Becker RO, Laplace plane analysis of impedance on the H meridian, The American journal of Chinese medicine, 1979 Summer;7(2):188-93, PMID: 484540
The AC impedance of a length of the H meridian not containing any acupuncture points was studied by means of Laplace plane analysis of the time domain response to an input voltage pulse. The ensuing frequency domain data were compared to the results of an identical analysis for two anatomically similar controls on either side of the meridian. The resistance of the meridian was significantly lower than either control.
Becker RO, The significance of electrically stimulated osteogenesis: more questions than answers, Clinical Orthopedics and Related Research, 1979 Jun;(141):266-74, PMID: 314373
The present technique of electrical osteogenesis represents the rediscovery of a method in clinical use over 100 years ago. That technique while reported to have excellent clinical results, was empirically applied and was totally discredited as having no scientific basis. Modern techniques report similarly useful clinical results, but similarly lack an accepted scientific basis. The techniques in present use differ so greatly among themselves that a common mechanism of action seems highly unlikely. Yet all report excellent clinical results. Serious questions are raised concerning the validity of the claims, the mechanism of action and the possibility of long-term undesirable side effects. These questions are not insoluble and the newer physical science disciplines seem well suited to reveal the mechanism of action. Appropriate research projects must be mounted and answers to these questions obtained before the technique is made available for wide application. The importance of this procedure far transcends orthopedic surgery and bone growth stimulation and if properly pursued, it may lead to revolutionary changes, not only in basic biology, but in the practice of clinical medicine in general.
Marino AA, Becker RO, Hart FX, Anders F Jr., Space osteoporosis: an electromagnetic hypothesis, Aviation, space, and environmental medicine, 1979 Apr;50(4):409-10, PMID: 464968
Loss of body calcium during spaceflight is a potential problem in long voyages. This loss does not appear to be caused by a deficiency in diet or exercise. The idea is advanced that the altered electromagnetic environment experienced in space may be at least partially responsible. We show that the electric field induced inside astronauts because of their motion in the geomagnetic field is greater than that which has produced a wide variety of biological effects in earth-bound experiments.
Reichmanis M, Perry FS, Marino AA, Becker RO, Relation between suicide and the electromagnetic field of overhead power lines, Physiological chemistry and physics, 1979;11(5):395-403, PMID: 542502
Laboratory studies have shown that electromagnetic fields similar to those from high-voltage transmission lines can produce biological effects. Surveys of the actual effects of such lines on exposed individuals usually have been hampered by complicating factors tending to blur the data. By means of a new approach, however, correlation has been established between the presence of transmission-line fields and the occurrence of suicides in part of the Midlands of England.
Becker RO, Electrical Osteogenesis: Pros and cons, Calcified tissue research, 1978 Dec 8;26(2):93-7, PMID: 367538
Becker RO, Spadaro JA, Treatment of orthopaedic infections with electrically generated silver ions. A preliminary report, The Journal of bone and joint surgery (American volume), 1978 Oct;60(7):871-81, PMID: 701335
Electrically generated silver ions have been shown previously to be a potent antibacterial agent with an exceptionally broad spectrum as indicated by in vitro testing. The present study reports on clinical experience using electrically generated silver ions as adjunctive treatment in the management of chronic osteomyelitis. Fourteen patients had fifteen treatment attempts: thirteen for chronic osteomyelitis of the tibia, one for acute and chronic pyarthrosis and osteomyelitis of the knee, and one for a chronically draining sinus after total hip replacement. Wound débridement, silver ion iontophoresis, and subsequent wound care (usually provided by the patient) resulted in control of the infection in twelve of the fifteen treatment attempts and in healing of the non-union after follow-up ranging from three to thirty-six months. The other three attempts led to two partial and one complete failure.
Reichmanis M, Becker RO, Physiological effects of stimulation at acupuncture loci: a review, Comparative medicine East and West, 1978 Spring;6(1):67-73, PMID: 710080
Recent studies reporting significant physiological effects associated with electrical and manual stimulation at several traditional Chinese acupuncture loci are reviewed. Other reports on the anatomy and electrical properties (DC resistance and potential, AC impedance) of these sites indicate that many are significant local skin resistance minima and may also be points of locally more positive DC potential. Further investigation of the basic properties of the acupuncture system and its mode of action is fully warranted by these preliminary findings.
Dueland R, Hoffer RE, Seleen WA, Becker RO, The effects of low voltage current on healing of thermal third degree wounds, The Cornell veterinarian, 1978 Jan;68(1):51-9, PMID: 303976
Bilateral third degree burns were created on the flanks of eight miniature swine. Each animal had one side treated daily with low intensity direct (LIDC) of 400 microamperes (muA) by contact electrode for 2 hours morning and afternoon until healing occurred. The polarity of the electrode was negative in 4 pigs and positive in 4 pigs. One group of 4 pigs had the eschar surgically removed 24 hours post burn. Weekly biopsies and cultures were taken of treated and control wounds. Results indicated: local treatment of 400 muA LIDC did not hasten or delay healing of thermal third degree burns; escharectomy hastened wound healing by 10 days, and superficial proteus infection occurred in 80% of all wounds.
Mitchell JT, Marino AA, Berger TJ, Becker RO, Effect of electrostatic fields on the chromosomes of Ehrlich ascites tumor cells exposed in vivo, Physiological chemistry and physics, 1978;10(1):79-85, PMID: 569338
An effect of electrostatic fields on the chromosomes of Ehrlich ascites tumor cells exposed in vivo has been demonstrated. Cells exposed to horizontal electrostatic fields for two weeks had almost a threefold increase in the percentage of abnormal chromosomes when compared to control cells or cells exposed to vertical electrostatic fields for the same period. Extended exposure times of 4–15 weeks resulted in the disappearance of the aberrant chromosomes. It is suggested that the effected cells were incapable of cellular replication resulting eventually in their disappearance via cell death.
Marino AA, Becker RO, Hazard at a distance: effects of exposure to the electric and magnetic fields of high voltage transmission lines, Medical research engineering, 1977 Nov;12(5):6-9, PMID: 349303
Reichmanis M, Marino AA, Becker RO, Laplace plane analysis of impedance between acupuncture points H-3 and H-4, Comparative medicine East and West, 1977 Fall-Winter;5(3-4):289-95, PMID: 610979
The frequency dependence of the skin impedance between two acupuncture points (H-3 and H-4) was determined by Laplace plane analysis of the time domain response to an input voltage perturbation. Both the resistance and capacitance between the acupuncture points differed significantly from the corresponding controls, thus supporting the interpretation of the acupuncture system as an information transfer network.
Reichmanis M, Becker RO, Relief of experimentally-induced pain by stimulation at acupuncture loci: a review, Comparative medicine East and West,1977 Fall-Winter;5(3-4):281-8, PMID: 610978
Reichmanis M, Marino AA, Becker RO, Laplace plane analysis of transient impedance between acupuncture points Li-4 and Li-12, IEEE transactions on bio-medical engineering, 1977 Jul;24(4):402-5, PMID: 881215
Becker RO, Spadaro JA, Marino AA, Clinical experiences with low intensity direct current stimulation of bone growth,Clinical Orthopedics and related research, 1977 May;(124):75-83, PMID: 304404
Low intensity direct current stimulation of bone growth involves the continuous application of cathodic currents in the nanoampere range. The technique has been applied to 13 patients with a variety of non-unions and pseudarthroses with a success rate of 77 per cent. Preliminary data indicate that a range of total energy, from 0.6 to 2.5 Joules, is maximally effective. The technique has been combined with anodic control of local bacterial infection with promising results. Both the osteogenic stimulation and the bacterial suppression techniques as described in this paper, appear to be safe and effective.
Marino AA, Becker RO, Electrical osteogenesis: an analysis, Clinical Orthopedics and related research, 1977 Mar-Apr;(123):280-2, PMID: 852183
Marino AA, Berger TJ, Austin BP, Becker RO, Hart FX, In vivo bioelectrochemical changes associated with exposure to extremely low frequency electric fields, Physiological chemistry and physics, 1977;9(4-5):433-41, PMID: 613333
One hundred seventy-four 21- to 24-day-old Sprague-Dawley rats were continuously exposed to a 60 Hz electric field of 150 V/cm for one month in ten separate experiments. Biological effects observed included depressed body weights, serum corticoids, and water consumption. The findings are tentatively in terpreted as indicating that a power frequency electric field is a biological stressor. The observed effects cannot be a consequence of Joule heating and therefore indicate that electric fields can influence biological systems either at the systemic level, or at the cellular level via electrochemical alteration of the microenvironment.
Marino AA, Becker RO, Biological effects of extremely low frequency electric and magnetic fields: a review, Physiological chemistry and physics, 1977;9(2):131-47, PMID: 414240
Berger TJ, Spadaro JA, Bierman R, Chapin SE, Becker RO, Antifungal properties of electrically generated metallic ions, Antimicrobial agents and chemotherapy, 1976 Nov;10(5):856-60, PMID: 1034467, PMCID: PMC429848
A qualitative and quantitative investigation was undertaken to study the susceptibility of unicellular eucaryotic organisms (yeasts) to metallic cations generated by low levels of direct current. Results were characteristic of effects obtained previously using clinical and standard bacteria test organisms. The present study demonstrated that anodic silver (Ag(+)) at low direct currents had inhibitory and fungicidal properties. Broth dilution susceptibility tests were made on several species of Candida and one species of Torulopsis. Growth in all isolates was inhibited by concentrations of electrically generated silver ions between 0.5 and 4.7 mug/ml, and silver exhibited fungicidal properties at concentrations as low as 1.9 mug/ml. The inhibitory and fungicidal concentrations of electrically generated silver ions are lower than those reported for other silver compounds.
Fuller RG, Marino AA, Becker RO, Photoconductivity in bone and tendon, Biophysical journal, 1976 Jul;16(7):845-6, PMID: 938723, PMCID: PMC1334905
Ultraviolet light can be used to stimulate electrical current flow in bone and tendon. This stimulated photocurrent is directional. In tendon the photocurrent parallel to the fibrils is greater than the photocurrent perpendicular to the fibrils. In bone, the longitudinal photocurrent is less than the transverse photocurrent.
Marino AA, Becker RO, Ullrich B, The effect of continuous exposure to low frequency electric fields on three generations of mice: a pilot study., Experientia, 1976 May 15;32(5):565-6, PMID: 1278293
Mice were allowed to mate, gestate, deliver and rear their offspring for 3 successive generations while being continuously exposed to 60 Hz electric fields. Mice exposed to vertical electric fields exhibited decreased body weights at 35 days postpartum and increased mortality rates for 3 successive generations. Mice exposed to horizontal electric fields exhibited decreased body weights for 2 successive generations.
Reichmanis M, Marino AA, Becker RO, D.C. skin conductance variation at acupuncture loci, The American journal of Chinese medicine, 1976 Spring;4(1):69-72, PMID: 1266803
Skin conductance was measured in 10 subjects with a DC Wheatstone bridge in 10 areas purportedly containing acupuncture loci on the Triple Burner (TB) and Lung (Lu) meridians. When the results were compared to those from anatomically similar locations devoid of acupuncture loci, local conductance variation was found to be significantly different (p less than 0.05) in most acupuncture locus locations.
Berger TJ, Spadaro JA, Chapin SE, Becker RO, Electrically generated silver ions: quantitative effects on bacterial and mammalian cells, Antimicrobial agents and chemotherapy, 1976 Feb;9(2):357-8, PMID: 944551
The inhibitory and bactericidal concentrations of electrically generated silver ions were 10 to 100 times lower than for silver sulfadiazine. Effects on normal mammalian cells were minimal.
Reichmanis M, Marino AA, Becker RO, Electrical correlates of acupuncture points, IEEE transactions on bio-medical engineering, 1975 Nov;22(6):533-5, PMID: 1184029
Marino AA, Becker RO, Piezoelectricity in hydrated frozen bone and tendon.Nature, 1974 Nov 15;30(11):1274-5, PMID: 4140104
Spadaro JA, Berger TJ, Barranco SD, Chapin SE, Becker RO, Antibacterial effects of silver electrodes with weak direct current, Antimicrobial agents and chemotherapy, 1974 Nov;6(5):637-42, PMID: 15825319, PMCID: PMC444706
Silver, platinum, gold, stainless-steel, and copper electrodes were used with low currents (0.02 to 20 muA/mm(2)) to explore their electrochemical effects on the growth of four bacterial species. In the higher current ranges, all electrodes inhibited growth at both poles, usually in conjunction with electrolytic break-down of the medium and severe corrosion of the metal. Silver, however, was extremely bacteriostatic, even at the lowest current, when used as the anode. Quantitative studies showed that most of this inhibition takes place in a few hours and is not accompanied by changes in pH. Electrochemically injected silver from the anode is probably the instrumental agent, being effective in concentrations of about 5 mug/ml. This is the equivalent concentration of silver sulfadiazine that has been shown to give complete inhibition of bacteria, but without the sulfonamide moiety.
Marino AA, Berger TJ, Becker RO, Spadaro JA, The effect of selected metals on marrow cells in culture, Chemico-biological interactions, 1974 Sep;9(3):217-23, PMID: 4426110
Baker B, Becker RO, Spadaro J, A study of electrochemical enhancement of articular cartilage repair, Clinical Orthopaedics and Related Research, 1974 Jul-Aug;(102):251-67, PMID: 4425033
Marino AA, Becker RO, Piezoelectricity in bone as a function of age, Calcified tissue research, 1974 May 28;14(4):327-31, PMID: 4527112
Barranco SD, Spadaro JA, Berger TJ, Becker RO, In vitro effect of weak direct current on Staphylococcus aureus, Clinical orthopaedics and related research, 1974 May;(100):250-5., PMID: 4838406
Marino AA, Becker RO, Piezoelectricity and autoinduction, Clinical orthopaedics and related research, 1974 May;(100):247-9, PMID: 4838405
Becker RO, Chapin S, Sherry R, Regeneration of the ventricular myocardium in amphibians, Nature, 1974 Mar 8;248(444):145-7, PMID: 4818918
Bassett CA, Becker RO, Brighton CT, Lavine L, Rowley BA, Panel discussion: To what extent can electrical stimulation be used in the treatment of human disorders?, Annals of the New York Academy of Sciences, 1974;238:586-93, PMID: 4548340
Baker B, Spadaro J, Marino A, Becker RO, Electrical stimulation of articular cartilage regeneration, Annals of the New York Academy of Sciences, 1974;238:491-9, PMID: 4548334
Becker RO, Cone CD, Jaffe LF, Parsegian VA, Pohl HA,Weiss L, Panel discussion: The role of electrical potential at the cellular level in growth and development, Annals of the New York Academy of Sciences, 1974;238:451-6, PMID: 4531274
Marino AA, Berger TJ, Mitchell JT, Duhacek BA, Becker RO, Electric field effects in selected biologic systems, Annals of the New York Academy of Sciences, 1974;238:436-44, PMID: 4531272
Becker RO, The basic biological data transmission and control system influenced by electrical forces, Annals of the New York Academy of Sciences, 1974;238:236-41, PMID: 4531264
Harrington DB, Becker RO, Electrical stimulation of RNA and protein synthesis in the frog erythrocyte, Experimental cell research, 1973 Jan;76(1):95-8, PMID: 4118777
Spadaro JA, Becker RO, Effects of thermal denaturation on metal binding and ultrastructure in collagen fibrils, Biochimica et biophysica acta, 1972 May 18;263(3):585-92, PMID: 5034209
Becker RO, Spadaro JA, Electrical stimulation of partial limb regeneration in mammals, Bulletin of the New York Academy of Medicine. 1972 May;48(4):627-41, PMID: 4503923, PMCID: PMC1806700
Becker RO, Augmentation of regenerative healing in man. A possible alternative to prosthetic implantation, Clinical orthopaedics and related research, 1972 Mar-Apr;83:255-62, PMID: 5014820
Berg E, Marino AA, Becker RO, Dupuytren’s contracture: some associated biophysical abnormalities, Clinical orthopaedics and related research, 1972 Mar-Apr;83:144-8, PMID: 4335505
Becker RO, Stimulation of partial limb regeneration in rats, Nature, 1972 Jan 14;235(5333):109-11, PMID: 4550399
Marino AA, Becker RO, Soderholm SC, Origin of the piezoelectric effect in bone, Calcified tissue research, 1971;8(2):177-80, PMID: 5145213
Becker RO, Murray DG, The electrical control system regulating fracture healing in amphibians, Clinical orthopaedics and related research,1970 Nov-Dec;73:169-98, PMID: 5479774
Marino A, Becker RO, Piezoelectric effect and growth control in bone, Nature, 1970 Oct 31;228(5270):473-4, PMID: 5482504
Marino AA, Becker RO, Evidence for epitaxy in the formation of collagen and apatite, Nature, 1970 May 16;226(5246):652-3, PMID: 4315552
Spadaro JA, Becker RO,Bachman CH, Size-specific metal complexing sites in native collagen, Nature, 1970 Mar 21;225(5238):1134-6, PMID: 4907289
Spadaro JA, Becker RO, Bachman CH, The distribution of trace metal ions in bone and tendon, Calcified tissue research, 1970;6(1):49-54, PMID: 5501380
Marino AA, Becker RO, The effect of electric current on rat tail tendon collagen in solution, Calcified tissue research, 1970;4(4):330-8, PMID: 4910253
Ellis EH, Spadaro JA, Becker RO, Trace elements in tendon collagen, Clinical orthopaedics and related research, 1969 Jul-Aug;65:195-8, PMID: 5802525
Marino AA, Becker RO, Temperature dependence of the EPR signal in tendon collage, Nature, 1969 Apr 12;222(5189):164-5, PMID: 4304924
Marino AA, Becker RO, Correction concerning electron paramagnetic resonance in human bone mineral, Nature, 1969 Feb 15;221(5181):661, PMID: 4304585
Marino AA, Becker RO, Mechanically induced free radicals in bone, Nature, 1968 May 4;218(5140):466-7, PMID: 4296985
Becker RO, Spadaro JA, Berg EW, The trace elements of human bone, The Journal of bone and joint surgery. American volume, 1968 Mar;50(2):326-34, PMID: 5642821
Marino AA, Becker RO, Bachman CH, Dielectric determination of bound water of bone, Physics in medicine and biology, 1967 Jul;12(3):367-78, PMID: 6036199
Becker RO, The electrical control of growth processes, Medical times, 1967 Jun;95(6):657-69, PMID: 6042257
Friedman H, Becker RO, Bachman CH, Effect of magnetic fields on reaction time performance, Nature, 1967 Mar 4;213(5079):949-50, PMID: 6030075
Becker RO, Murray DG, A method for producing cellular dedifferentiation by means of very small electrical currents, Transactions of the New York Academy of Sciences, 1967 Mar;29(5):606-15, PMID: 5235589
Marino AA, Becker RO, Evidence for direct physical bonding between the collagen fibres and apatite cystals in bone, Nature, 1967 Feb 18;213(5077):697-8, PMID: 4291695
Becker RO, Marino AA, Electron paramagnetic resonance spectra of bone and its major components, Nature, 1966 May 7;210(5036):583-8, PMID: 4290190
Becker RO, The control system governing bone growth in response to mechanical stress, The Journal of the Arkansas Medical Society, 1966 Mar;62(10):404-6, PMID: 4221948
Becker RO, Bachman CH, Bioelectric effects in tissue, Clinical orthopaedics and related research, 1965 Nov-Dec;43:251-3, PMID: 5861096
Becker RO, Brown FM, Photoelectric effects in human bone, Nature, 1965 Jun 26;206(991):1325-8, PMID: 5839595
BASSETT CA, PAWLUK RJ, BECKER RO, EFFECTS OF ELECTRIC CURRENTS ON BONE IN VIVO, Nature, 1964 Nov 14;204:652-4, PMID: 14236279
BACHMAN CH, BECKER RO, FRIEDMAN H, THE GRADED BOUNDARY CARBON-SALINE ELECTRODE, Perceptual and motor skills, 1964 Aug;19:67-73, PMID: 14198858
FRIEDMAN H, BECKER RO, BACHMAN CH, GEOMAGNETIC PARAMETERS AND PSYCHIATRIC HOSPITAL ADMISSIONS, Nature, 1963 Nov 16;200:626-8, PMID: 14109937
BECKER RO., ELECTRON PARAMAGNETIC RESONANCE IN NON-IRRADIATED BONE, Nature, 1963 Sep 28;199:1304-5, PMID: 14074611
BECKER RO, Relationship of geomagnetic environment to human biology, New York state journal of medicine, 1963 Aug 1;63:2215-9, PMID: 13970135
BECKER RO, BACHMAN CH, SLAUGHTER WH, Longitudinal direct-current gradients of spinal nerves, Nature, 1962 Nov 17;196:675-6 PMID: 13970134
BASSETT CA, BECKER RO, Generation of electric potentials by bone in response to mechanical stress, Science, 1962 Sep 28;137:1063-4, PMID: 13865637
The amplitude of electrical potentials generated in stressed bone is dependent upon the rate and magnitude of bony deformation, while polarity is determined by the direction of bending. Areas under compression develop negative potentials with respect to other areas. Similar results were obtained both in living and dead bone. Removal of the inorganic fraction from bone abolishes its ability to generate stress potentials. It is probable that these potentials influence the activity of osseous cells directly. Furthermore, it is conceivable that they may direct, in some manner, the aggregation pattern of the macromolecules of the extracellular matrix.
FRIEDMAN H, BECKER RO, BACHMAN CH, Direct current potentials in hypnoanalgesia, Archives of general psychiatry, 1962 Sep;7:193-7, PMID: 13895255
BECKER RO, BACHMAN CH, FRIEDMAN H, The direct current control system. A link between environment and organism, New York state journal of medicine, 1962 Apr 15;62:1169-76, PMID: 13866365
Becker RO, Search for Evidence of Axial Current Flow in Peripheral Nerves of Salamander, Science, 1961 Jul 14;134(3472):101-10, PMID: 17807392
The demonstrated association of the d-c bioelectric field with central nervous system elements implies the longitudinal flow of charge carriers within that system. Transverse d-c voltages, attributed to the Hall effect, have been obtained from the extremities of intact salamanders under circumstances suggesting such electric current. These voltages disappeared after nerve section, and their magnitude was related to the depth of anesthesia.
ROBERT O. BECKER, The bioelectric factors in amphibian-limb regeneration, The Journal of bone and joint surgery American volume, 1961 Jul;43-A:643-56, PMID: 14448529
BECKER ROBERT O., The bioelectric field pattern in the salamander and its simulation by an electronic analog, IRE transactions on medical electronics, 1960 Jul;ME-7:202-7, PMID: 13688481
BECKER ROBERT O, CHAMBERLIN JT, A modified coaxial electrode for electromyography, Archives of physical medicine and rehabilitation, 1960 Apr;41:149-51, PMID: 13798116
BECKER ROBERT O., The electrical response of human skeletal muscle to passive stretch, Surgical forum, 1960;10:828-31, PMID: 13798117
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